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Dean  Li
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Dean Li

Selected Publications

Nguyen QC, Meng H, Li D, Kath S, McCullough M, Paul D, Kanokvimankul P, Nguyen TX, Li F, Social media indicators of the food environment and state health outcomes. Public Health 2017 Jul;148:120-128

Tai-Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, Ieda M, Takakura N, Nakagawa O, Zhou B, Okabayashi K, Suematsu M, Kitagawa Y, Bastmeyer M, Sato K, Klein R, Navankasattusas S, Li DY, Yamagishi S, Kubota Y, Placental labyrinth formation in mice requires endothelial FLRT2-UNC5B signaling. Development 2017 Jun 2;:

Tang AT, Choi JP, Kotzin JJ, Yang Y, Hong CC, Hobson N, Girard R, Zeineddine HA, Lightle R, Moore T, Cao Y, Shenkar R, Chen M, Mericko P, Yang J, Li L, Tanes C, Kobuley D, Võsa U, Whitehead KJ, Li DY, Franke L, Hart B, Schwaninger M, Henao-Mejia J, Morris, Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature 2017 May 18;545(7654):305-310

Cova TJ, Dennison PE, Li D, Drews FA, Siebeneck LK, Lindell MK, Warning Triggers in Environmental Hazards: Who Should Be Warned to Do What and When? Risk Anal 2017 Apr;37(4):601-611

Seidel T, Navankasattusas S, Ahmad A, Diakos NA, Xu WD, Tristani-Firouzi M, Bonios MJ, Taleb I, Li DY, Selzman CH, Drakos SG, Sachse FB, Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading. Circulation 2017 Apr 25;135(17):1632-1645

Grossmann AH, Zhao H, Jenkins N, Zhu W, Richards JR, Yoo JH, Winter JM, Rich B, Mleynek TM, Li DY, Odelberg SJ, The small GTPase ARF6 regulates protein trafficking to control cellular function during development and in disease. Small GTPases 2016 Dec 21;:1-12

Diakos NA, Navankasattusas S, Abel ED, Rutter J, McCreath L, Ferrin P, McKellar SH, Miller DV, Park SY, Richardson RS, Deberardinis R, Cox JE, Kfoury AG, Selzman CH, Stehlik J, Fang JC, Li DY, Drakos SG, Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning. JACC Basic Transl Sci 2016 Oct;1(6):432-444

Nguyen QC, Li D, Meng HW, Kath S, Nsoesie E, Li F, Wen M, Building a National Neighborhood Dataset From Geotagged Twitter Data for Indicators of Happiness, Diet, and Physical Activity. JMIR Public Health Surveill 2016 Oct 17;2(2):e158

Wever-Pinzon O, Drakos SG, McKellar SH, Horne BD, Caine WT, Kfoury AG, Li DY, Fang JC, Stehlik J, Selzman CH, Cardiac Recovery During Long-Term Left Ventricular Assist Device Support. J Am Coll Cardiol 2016 Oct 4;68(14):1540-53

Zhao H, Mleynek TM, Li DY, Dysregulated exocytosis of angiopoietin-2 drives cerebral cavernous malformation. Nat Med 2016 Sep 7;22(9):971-3

Nguyen QC, Kath S, Meng HW, Li D, Smith KR, VanDerslice JA, Wen M, Li F, Leveraging geotagged Twitter data to examine neighborhood happiness, diet, and physical activity. Appl Geogr 2016 Aug;73:77-88

Han P, Li W, Yang J, Shang C, Lin CH, Cheng W, Hang CT, Cheng HL, Chen CH, Wong J, Xiong Y, Zhao M, Drakos SG, Ghetti A, Li DY, Bernstein D, Chen HS, Quertermous T, Chang CP, Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts. Biochim Biophys Acta 2016 Jul;1863(7 Pt B):1772-81

Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY, ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma. Cancer Cell 2016 Jun 13;29(6):889-904

Zhou Z, Tang AT, Wong WY, Bamezai S, Goddard LM, Shenkar R, Zhou S, Yang J, Wright AC, Foley M, Arthur JS, Whitehead KJ, Awad IA, Li DY, Zheng X, Kahn ML, Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature 2016 Apr 7;532(7597):122-6

Zhao H, Ahirwar DK, Oghumu S, Wilkie T, Powell CA, Nasser MW, Satoskar AR, Li DY, Ganju RK, Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis. Mol Oncol 2016 Feb;10(2):272-81

Choi JP, Foley M, Zhou Z, Wong WY, Gokoolparsadh N, Arthur JS, Li DY, Zheng X, Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice. PLoS One 2016;11(8):e0160833

Song NJ, Kim S, Jang BH, Chang SH, Yun UJ, Park KM, Waki H, Li DY, Tontonoz P, Park KW, Small Molecule-Induced Complement Factor D (Adipsin) Promotes Lipid Accumulation and Adipocyte Differentiation. PLoS One 2016;11(9):e0162228

Girard R, Khanna O, Shenkar R, Zhang L, Wu M, Jesselson M, Zeineddine HA, Gangal A, Fam MD, Gibson CC, Whitehead KJ, Li DY, Liao JK, Shi C, Awad IA, Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease. Biomark Med 2016;10(3):255-64

Koening CL, Peterson SG, Podnecky NL, Schweizer HP, Li DY, Katz BJ, Absence of Bacteria in the Temporal Arteries of Patients with Giant Cell Arteritis. J Clin Rheumatol 2016 Jan;22(1):43-4

Cahoon JM, Rai RR, Carroll LS, Uehara H, Zhang X, O'Neil CL, Medina RJ, Das SK, Muddana SK, Olson PR, Nielson S, Walker K, Flood MM, Messenger WB, Archer BJ, Barabas P, Krizaj D, Gibson CC, Li DY, Koh GY, Gao G, Stitt AW, Ambati BK, Intravitreal AAV2.COMP-Ang1 Prevents Neurovascular Degeneration in a Murine Model of Diabetic Retinopathy. Diabetes 2015 Dec;64(12):4247-59

Feng FT, Cui Q, Liu WS, Guo YM, Feng QS, Chen LZ, Xu M, Luo B, Li DJ, Hu LF, Middeldorp JM, Ramayanti O, Tao Q, Cao SM, Jia WH, Bei JX, Zeng YX, A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma. Chin J Cancer 2015 Dec 16;34(12):563-72

Thompson J, Verma D, Li D, Mosbruger T, Swaminathan S, Identification and Characterization of the Physiological Gene Targets of the Essential Lytic Replicative Epstein-Barr Virus SM Protein. J Virol 2015 Nov 11;90(3):1206-21

Rahman M, Jackson LK, Johnson WE, Li DY, Bild AH, Piccolo SR, Alternative preprocessing of RNA-Sequencing data in The Cancer Genome Atlas leads to improved analysis results. Bioinformatics 2015 Nov 15;31(22):3666-72

Li YR, Zhao SD, Li J, Bradfield JP, Mohebnasab M, Steel L, Kobie J, Abrams DJ, Mentch FD, Glessner JT, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Li D, Maggadottir SM, Thomas KA, Qui H, Chiavacci RM, Kim CE, Wang F, Snyder J, Flatø B, Førre Ø, Dens, Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nat Commun 2015 Oct 9;6:8442

Bauer DW, Li D, Huffman J, Homa FL, Wilson K, Leavitt JC, Casjens SR, Baines J, Evilevitch A, Exploring the Balance between DNA Pressure and Capsid Stability in Herpesviruses and Phages. J Virol 2015 Sep;89(18):9288-98

Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Glessner JT, Li D, Kao C, Thomas KA, Qiu H, Chiavacci RM, Kim CE, Wang F, Snyder J, Richie MD, Flatø B, Førr, Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nat Med 2015 Sep;21(9):1018-27

Zhen DB, Rabe KG, Gallinger S, Syngal S, Schwartz AG, Goggins MG, Hruban RH, Cote ML, McWilliams RR, Roberts NJ, Cannon-Albright LA, Li D, Moyes K, Wenstrup RJ, Hartman AR, Seminara D, Klein AP, Petersen GM, BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study. Genet Med 2015 Jul;17(7):569-77

Qi Q, Li DY, Luo HR, Guan KL, Ye K, Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability. Proc Natl Acad Sci U S A 2015 Jun 9;112(23):7255-60

Lawton MT, Rutledge WC, Kim H, Stapf C, Whitehead KJ, Li DY, Krings T, terBrugge K, Kondziolka D, Morgan MK, Moon K, Spetzler RF, Brain arteriovenous malformations. Nat Rev Dis Primers 2015 May 28;1:15008

Walker AE, Henson GD, Reihl KD, Morgan RG, Dobson PS, Nielson EI, Ling J, Mecham RP, Li DY, Lesniewski LA, Donato AJ, Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness. J Physiol 2015 Apr 15;593(8):1931-43

Verma D, Li DJ, Krueger B, Renne R, Swaminathan S, Identification of the physiological gene targets of the essential lytic replicative Kaposi's sarcoma-associated herpesvirus ORF57 protein. J Virol 2015 Feb;89(3):1688-702

MacNeil SM, Johnson WE, Li DY, Piccolo SR, Bild AH, Inferring pathway dysregulation in cancers from multiple types of omic data. Genome Med 2015;7(1):61

Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML, The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression. Dev Cell 2015 Jan 26;32(2):168-80

Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY, Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation. Circulation 2015 Jan 20;131(3):289-99

Gibson CC, Davis CT, Zhu W, Bowman-Kirigin JA, Walker AE, Tai Z, Thomas KR, Donato AJ, Lesniewski LA, Li DY, Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium. PLoS One 2015;10(10):e0140370

Mleynek TM, Chan AC, Redd M, Gibson CC, Davis CT, Shi DS, Chen T, Carter KL, Ling J, Blanco R, Gerhardt H, Whitehead K, Li DY, Lack of CCM1 induces hypersprouting and impairs response to flow. Hum Mol Genet 2014 Dec 1;23(23):6223-34

Abdullah OM, Drakos SG, Diakos NA, Wever-Pinzon O, Kfoury AG, Stehlik J, Selzman CH, Reid BB, Brunisholz K, Verma DR, Myrick C, Sachse FB, Li DY, Hsu EW, Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological validation. NMR Biomed 2014 Nov;27(11):1378-86

Donato AJ, Lesniewski LA, Stuart D, Walker AE, Henson G, Sorensen L, Li D, Kohan DE, Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development. Life Sci 2014 Nov 24;118(2):238-43

Diakos NA, Selzman CH, Sachse FB, Stehlik J, Kfoury AG, Wever-Pinzon O, Catino A, Alharethi R, Reid BB, Miller DV, Salama M, Zaitsev AV, Shibayama J, Li H, Fang JC, Li DY, Drakos SG, Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery. J Am Coll Cardiol 2014 Oct 14;64(15):1602-12

Davis CT, Zhu W, Gibson CC, Bowman-Kirigin JA, Sorensen L, Ling J, Sun H, Navankasattusas S, Li DY, ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock. J Immunol 2014 Jun 15;192(12):6045-52

Frech T, De Domenico I, Murtaugh MA, Revelo MP, Li DY, Sawitzke AD, Drakos S, Autophagy is a key feature in the pathogenesis of systemic sclerosis. Rheumatol Int 2014 Mar;34(3):435-9

Wang H, Jiang Y, Shi D, Quilliam LA, Chrzanowska-Wodnicka M, Wittchen ES, Li DY, Hartnett ME, Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization. FASEB J 2014 Jan;28(1):265-74

Li DJ, Verma D, Mosbruger T, Swaminathan S, CTCF and Rad21 act as host cell restriction factors for Kaposi's sarcoma-associated herpesvirus (KSHV) lytic replication by modulating viral gene transcription. PLoS Pathog 2014 Jan;10(1):e1003880

Mleynek TM, Li D, Maintaining the plexus: SYNJ2BP as a novel regulator of angiogenesis. Circ Res 2013 Nov 8;113(11):1186-8

Yang M, Odelberg SJ, Tong Z, Li DY, Looper RE, Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas. Tetrahedron 2013 Jul 8;69(27-28):5744-5750

Luo L, Uehara H, Zhang X, Das SK, Olsen T, Holt D, Simonis JM, Jackman K, Singh N, Miya TR, Huang W, Ahmed F, Bastos-Carvalho A, Le YZ, Mamalis C, Chiodo VA, Hauswirth WW, Baffi J, Lacal PM, Orecchia A, Ferrara N, Gao G, Young-Hee K, Fu Y, Owen L, Albuque, Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. Elife 2013 Jun 18;2:e00324

Drakos SG, Wever-Pinzon O, Selzman CH, Gilbert EM, Alharethi R, Reid BB, Saidi A, Diakos NA, Stoker S, Davis ES, Movsesian M, Li DY, Stehlik J, Kfoury AG, Magnitude and time course of changes induced by continuous-flow left ventricular assist device unloading in chronic heart failure: insights into cardiac recovery. J Am Coll Cardiol 2013 May 14;61(19):1985-94

Wever-Pinzon O, Selzman CH, Drakos SG, Saidi A, Stoddard GJ, Gilbert EM, Labedi M, Reid BB, Davis ES, Kfoury AG, Li DY, Stehlik J, Bader F, Pulsatility and the risk of nonsurgical bleeding in patients supported with the continuous-flow left ventricular assist device HeartMate II. Circ Heart Fail 2013 May;6(3):517-26

Grossmann AH, Yoo JH, Clancy J, Sorensen LK, Sedgwick A, Tong Z, Ostanin K, Rogers A, Grossmann KF, Tripp SR, Thomas KR, D'Souza-Schorey C, Odelberg SJ, Li DY, The small GTPase ARF6 stimulates ß-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis. Sci Signal 2013 Mar 5;6(265):ra14

Whitehead KJ, Smith MC, Li DY, Arteriovenous malformations and other vascular malformation syndromes. Cold Spring Harb Perspect Med 2013 Feb 1;3(2):a006635

Wever-Pinzon O, Drakos SG, Kfoury AG, Nativi JN, Gilbert EM, Everitt M, Alharethi R, Brunisholz K, Bader FM, Li DY, Selzman CH, Stehlik J, Morbidity and mortality in heart transplant candidates supported with mechanical circulatory support: is reappraisal of the current United network for organ sharing thoracic organ allocation policy justified? Circulation 2013 Jan 29;127(4):452-62

Zhu W, London NR, Gibson CC, Davis CT, Tong Z, Sorensen LK, Shi DS, Guo J, Smith MC, Grossmann AH, Thomas KR, Li DY, Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability. Nature 2012 Dec 13;492(7428):252-5

Li DJ, Verma D, Swaminathan S, Binding of cellular export factor REF/Aly by Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 protein is not required for efficient KSHV lytic replication. J Virol 2012 Sep;86(18):9866-74

Frech TM, Revelo MP, Drakos SG, Murtaugh MA, Markewitz BA, Sawitzke AD, Li DY, Vascular leak is a central feature in the pathogenesis of systemic sclerosis. J Rheumatol 2012 Jul;39(7):1385-91

Chaudhuri D, Li D, Sigmund E, Wettach H, Höger S, Lupton JM, Plasmonic surface enhancement of dual fluorescence and phosphorescence emission from organic semiconductors: effect of exchange gap and spin-orbit coupling. Chem Commun (Camb) 2012 Jul 7;48(53):6675-7

Drakos SG, Kfoury AG, Stehlik J, Selzman CH, Reid BB, Terrovitis JV, Nanas JN, Li DY, Bridge to recovery: understanding the disconnect between clinical and biological outcomes. Circulation 2012 Jul 10;126(2):230-41

Jones CF, Campbell RA, Franks Z, Gibson CC, Thiagarajan G, Vieira-de-Abreu A, Sukavaneshvar S, Mohammad SF, Li DY, Ghandehari H, Weyrich AS, Brooks BD, Grainger DW, Cationic PAMAM dendrimers disrupt key platelet functions. Mol Pharm 2012 Jun 4;9(6):1599-611

Wever-Pinzon O, Stehlik J, Kfoury AG, Terrovitis JV, Diakos NA, Charitos C, Li DY, Drakos SG, Ventricular assist devices: pharmacological aspects of a mechanical therapy. Pharmacol Ther 2012 May;134(2):189-99

Larrieu-Lahargue F, Thomas KR, Li DY, Netrin ligands and receptors: lessons from neurons to the endothelium. Trends Cardiovasc Med 2012 Feb;22(2):44-7

Li D, Truong TV, Bills TM, Holt BC, VanDerwerken DN, Williams JR, Acharya A, Robison RA, Tolley HD, Lee ML, GC/MS method for positive detection of Bacillus anthracis endospores. Anal Chem 2012 Feb 7;84(3):1637-44

Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY, Netrin-4 activates endothelial integrin {alpha}6{beta}1. Circ Res 2011 Sep 16;109(7):770-4

Wythe JD, Jurynec MJ, Urness LD, Jones CA, Sabeh MK, Werdich AA, Sato M, Yost HJ, Grunwald DJ, Macrae CA, Li DY, Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Dis Model Mech 2011 Sep;4(5):607-21

Lim AH, Suli A, Yaniv K, Weinstein B, Li DY, Chien CB, Motoneurons are essential for vascular pathfinding. Development 2011 Sep;138(17):3847-57

Shi Y, Qu J, Zhang D, Zhao P, Zhang Q, Tam POS, Sun L, Zuo X, Zhou X, Xiao X, Hu J, Li Y, Cai L, Liu X, Lu F, Liao S, Chen B, He F, Gong B, Lin H, Ma S, Cheng J, Zhang J, Chen Y, Zhao F, Yang X, Chen Y, Yang C, Lam DSC, Li X, Shi F, Wu Z, Lin Y, Yang J, L, Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. Am J Hum Genet 2011 Jun 10;88(6):805-813

Chan AC, Drakos SG, Ruiz OE, Smith AC, Gibson CC, Ling J, Passi SF, Stratman AN, Sacharidou A, Revelo MP, Grossmann AH, Diakos NA, Davis GE, Metzstein MM, Whitehead KJ, Li DY, Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice. J Clin Invest 2011 May;121(5):1871-81

Drakos SG, Kfoury AG, Selzman CH, Verma DR, Nanas JN, Li DY, Stehlik J, Left ventricular assist device unloading effects on myocardial structure and function: current status of the field and call for action. Curr Opin Cardiol 2011 May;26(3):245-55

London NR, Li DY, Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm. Curr Opin Hematol 2011 May;18(3):186-90

Chaudhuri D, Li D, Che Y, Shafran E, Gerton JM, Zang L, Lupton JM, Enhancing long-range exciton guiding in molecular nanowires by H-aggregation lifetime engineering. Nano Lett 2011 Feb 9;11(2):488-92

Wilson BD, Gibson CC, Sorensen LK, Guilhermier MY, Clinger M, Kelley LL, Shiu YT, Li DY, Novel approach for endothelializing vascular devices: understanding and exploiting elastin-endothelial interactions. Ann Biomed Eng 2011 Jan;39(1):337-46

Li DY, Whitehead KJ, Evaluating strategies for the treatment of cerebral cavernous malformations. Stroke 2010 Oct;41(10 Suppl):S92-4

Gowen BB, Julander JG, London NR, Wong MH, Larson D, Morrey JD, Li DY, Bray M, Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. Virol J 2010 Sep 16;7:240

Kotter JR, Drakos SG, Horne BD, Hammond EH, Stehlik J, Bull DA, Reid BB, Gilbert EM, Everitt M, Alharethi R, Budge D, Verma DR, Li DY, Kfoury AG, Effect of blood product transfusion-induced tolerance on incidence of cardiac allograft rejection. Transplant Proc 2010 Sep;42(7):2687-92

De Domenico I, Zhang TY, Koening CL, Branch RW, London N, Lo E, Daynes RA, Kushner JP, Li D, Ward DM, Kaplan J, Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice. J Clin Invest 2010 Jul;120(7):2395-405

Drakos SG, Kfoury AG, Hammond EH, Reid BB, Revelo MP, Rasmusson BY, Whitehead KJ, Salama ME, Selzman CH, Stehlik J, Clayson SE, Bristow MR, Renlund DG, Li DY, Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart. J Am Coll Cardiol 2010 Jul 27;56(5):382-91

Greish K, Frandsen J, Scharff S, Gustafson J, Cappello J, Li D, O'Malley BW Jr, Ghandehari H, Silk-elastinlike protein polymers improve the efficacy of adenovirus thymidine kinase enzyme prodrug therapy of head and neck tumors. J Gene Med 2010 Jul;12(7):572-9

Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY, Netrin-4 induces lymphangiogenesis in vivo. Blood 2010 Jul 1;115(26):5418-26

Smith MC, Li DY, Whitehead KJ, Mechanisms of vascular stability and the relationship to human disease. Curr Opin Hematol 2010 May;17(3):237-44

Drakos SG, Janicki L, Horne BD, Kfoury AG, Reid BB, Clayson S, Horton K, Haddad F, Li DY, Renlund DG, Fisher PW, Risk factors predictive of right ventricular failure after left ventricular assist device implantation. Am J Cardiol 2010 Apr 1;105(7):1030-5

Chan AC, Li DY, Berg MJ, Whitehead KJ, Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype. FEBS J 2010 Mar;277(5):1076-83

London NR, Zhu W, Bozza FA, Smith MC, Greif DM, Sorensen LK, Chen L, Kaminoh Y, Chan AC, Passi SF, Day CW, Barnard DL, Zimmerman GA, Krasnow MA, Li DY, Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza. Sci Transl Med 2010 Mar 17;2(23):23ra19

Jones CA, Nishiya N, London NR, Zhu W, Sorensen LK, Chan AC, Lim CJ, Chen H, Zhang Q, Schultz PG, Hayallah AM, Thomas KR, Famulok M, Zhang K, Ginsberg MH, Li DY, Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity. Nat Cell Biol 2009 Nov;11(11):1325-31

Drakos SG, Kfoury AG, Kotter JR, Reid BB, Clayson SE, Selzman CH, Stehlik J, Fisher PW, Merida M 3rd, Eckels DD, Brunisholz K, Horne BD, Stoker S, Li DY, Renlund DG, Prior human leukocyte antigen-allosensitization and left ventricular assist device type affect degree of post-implantation human leukocyte antigen-allosensitization. J Heart Lung Transplant 2009 Aug;28(8):838-42

Sun X, Li D, Lee ML, Poly(ethylene glycol)-functionalized polymeric microchips for capillary electrophoresis. Anal Chem 2009 Aug 1;81(15):6278-84

Greish K, Araki K, Li D, O'Malley BW Jr, Dandu R, Frandsen J, Cappello J, Ghandehari H, Silk-elastinlike protein polymer hydrogels for localized adenoviral gene therapy of head and neck tumors. Biomacromolecules 2009 Aug 10;10(8):2183-8

London NR, Smith MC, Li DY, Emerging mechanisms of vascular stabilization. J Thromb Haemost 2009 Jul;7 Suppl 1:57-60

Whitehead KJ, Chan AC, Navankasattusas S, Koh W, London NR, Ling J, Mayo AH, Drakos SG, Jones CA, Zhu W, Marchuk DA, Davis GE, Li DY, The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases. Nat Med 2009 Feb;15(2):177-84

London NR, Whitehead KJ, Li DY, Endogenous endothelial cell signaling systems maintain vascular stability. Angiogenesis 2009;12(2):149-58

Zhang J, Chiang FI, Wu L, Czyryca PG, Li D, Chang CW, Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. J Med Chem 2008 Dec 11;51(23):7563-73

Yockman JW, Kastenmeier A, Erickson HM, Brumbach JG, Whitten MG, Albanil A, Li DY, Kim SW, Bull DA, Novel polymer carriers and gene constructs for treatment of myocardial ischemia and infarction. J Control Release 2008 Dec 18;132(3):260-6

Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY, Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat Med 2008 Apr;14(4):448-53

Navankasattusas S, Whitehead KJ, Suli A, Sorensen LK, Lim AH, Zhao J, Park KW, Wythe JD, Thomas KR, Chien CB, Li DY, The netrin receptor UNC5B promotes angiogenesis in specific vascular beds. Development 2008 Feb;135(4):659-67

Jones CA, Li DY, Common cues regulate neural and vascular patterning. Curr Opin Genet Dev 2007 Aug;17(4):332-6

Lu X, Li D, Dalley NK, Wood SG, Owen NL, Structure elucidation of compounds extracted from the Chinese medicinal plant Patrinia heterophylla. Nat Prod Res 2007 Jul 10;21(8):677-85

Wilson BD, Ii M, Park KW, Suli A, Sorensen LK, Larrieu-Lahargue F, Urness LD, Suh W, Asai J, Kock GA, Thorne T, Silver M, Thomas KR, Chien CB, Losordo DW, Li DY, Netrins promote developmental and therapeutic angiogenesis. Science 2006 Aug 4;313(5787):640-4

Park KW, Urness LD, Senchuk MM, Colvin CJ, Wythe JD, Chien CB, Li DY, Identification of new netrin family members in zebrafish: developmental expression of netrin 2 and netrin 4. Dev Dyn 2005 Nov;234(3):726-31

Park KW, Crouse D, Lee M, Karnik SK, Sorensen LK, Murphy KJ, Kuo CJ, Li DY, The axonal attractant Netrin-1 is an angiogenic factor. Proc Natl Acad Sci U S A 2004 Nov 16;101(46):16210-5

Whitehead KJ, Plummer NW, Adams JA, Marchuk DA, Li DY, Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations. Development 2004 Mar;131(6):1437-48

Urness LD, Li DY, Wiring the vascular circuitry: from growth factors to guidance cues. Curr Top Dev Biol 2004;62:87-126

Park KW, Morrison CM, Sorensen LK, Jones CA, Rao Y, Chien CB, Wu JY, Urness LD, Li DY, Robo4 is a vascular-specific receptor that inhibits endothelial migration. Dev Biol 2003 Sep 1;261(1):251-67

Sorensen LK, Brooke BS, Li DY, Urness LD, Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor. Dev Biol 2003 Sep 1;261(1):235-50

Karnik SK, Wythe JD, Sorensen L, Brooke BS, Urness LD, Li DY, Elastin induces myofibrillogenesis via a specific domain, VGVAPG. Matrix Biol 2003 Sep;22(5):409-25

Brooke BS, Bayes-Genis A, Li DY, New insights into elastin and vascular disease. Trends Cardiovasc Med 2003 Jul;13(5):176-81

Brooke BS, Karnik SK, Li DY, Extracellular matrix in vascular morphogenesis and disease: structure versus signal. Trends Cell Biol 2003 Jan;13(1):51-6

Karnik SK, Brooke BS, Bayes-Genis A, Sorensen L, Wythe JD, Schwartz RS, Keating MT, Li DY, A critical role for elastin signaling in vascular morphogenesis and disease. Development 2003 Jan;130(2):411-23

Urness LD, Sorensen LK, Li DY, Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet 2000 Nov;26(3):328-31

Wendel DP, Taylor DG, Albertine KH, Keating MT, Li DY, Impaired distal airway development in mice lacking elastin. Am J Respir Cell Mol Biol 2000 Sep;23(3):320-6

Gromova AS, Lutsky VI, Li D, Wood SG, Owen NL, Semenov AA, Grant DM, Thalicosides A1-A3, minor cycloartane bisdesmosides from Thalictrum minus. J Nat Prod 2000 Jul;63(7):911-4

Li DY, Sorensen LK, Brooke BS, Urness LD, Davis EC, Taylor DG, Boak BB, Wendel DP, Defective angiogenesis in mice lacking endoglin. Science 1999 May 28;284(5419):1534-7

Li DY, Faury G, Taylor DG, Davis EC, Boyle WA, Mecham RP, Stenzel P, Boak B, Keating MT, Novel arterial pathology in mice and humans hemizygous for elastin. J Clin Invest 1998 Nov 15;102(10):1783-7

Li DY, Brooke B, Davis EC, Mecham RP, Sorensen LK, Boak BB, Eichwald E, Keating MT, Elastin is an essential determinant of arterial morphogenesis. Nature 1998 May 21;393(6682):276-80

Li DY, Toland AE, Boak BB, Atkinson DL, Ensing GJ, Morris CA, Keating MT, Elastin point mutations cause an obstructive vascular disease, supravalvular aortic stenosis. Hum Mol Genet 1997 Jul;6(7):1021-8

Liu Z, Li D, Owen NL, Grant DM, Cates RG, Jia Z, Triterpenoid saponins from Gypsophila oldhamiana. J Nat Prod 1995 Oct;58(10):1632-5

Liu Z, Li D, Owen NL, Grant DM, Cates RG, Jia Z, Oleanane triterpene saponins from the Chinese medicinal herb Clinopodium chinensis. J Nat Prod 1995 Oct;58(10):1600-4

Sheffield MJ, Baker BL, Li D, Owen NL, Baker ML, Bell JD, Enhancement of Agkistrodon piscivorus piscivorus venom phospholipase A2 activity toward phosphatidylcholine vesicles by lysolecithin and palmitic acid: studies with fluorescent probes of membrane structure. Biochemistry 1995 Jun 20;34(24):7796-806

Li D, Owen NL, Perera P, Andersson C, Bohlin L, Cox PA, Pugmire RJ, Mayne CL, Grant DM, Structure elucidation of three triterpenoid saponins from Alphitonia zizyphoides using 2D NMR techniques. J Nat Prod 1994 Feb;57(2):218-24

Dunkel R, Mayne CL, Foster MP, Ireland CM, Li D, Owen NL, Pugmire RJ, Grant DM, Applications of the improved computerized analysis of 2D INADEQUATE spectra. Anal Chem 1992 Dec 15;64(24):3150-60