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Harriet  Hopf

Phone: 801-581-6393

Harriet Hopf

Professor of Anesthesiology
Adjunct Professor of Bioengineering
Faculty, Center on Aging
Director, Women in Medicine and Science Program (SOM)
Director of Mentoring for Office of Faculty Administration (SOM)
Adjunct Professor, Bioengineering
BA, Biology, Yale 1982
MD, Dartmouth Medical School 1986


Measurement of wound and other tissue oxgyen; prevention of surgicla site infection; genetics of health care associated infection

Selected Publications

Akca O, Ball L, Belda FJ, Biro P, Cortegiani A, Eden A, Ferrando C, Gattinoni L, Goldik Z, Gregoretti C, Hachenberg T, Hedenstierna G, Hopf HW, Hunt TK, Pelosi P, Qadan M, Sessler DI, Soro M, Sentürk M, WHO Needs High FIO2? Turk J Anaesthesiol Reanim 2017 Aug;45(4):181-192

Leslie K, Hopf HW, Houston P, O'Sullivan E, Women, Minorities, and Leadership in Anesthesiology: Take the Pledge. Anesth Analg 2017 May;124(5):1394-1396

Hopf HW, Preventing Opioid-Induced Postoperative Hypoxemia: No Simple Answer? Anesth Analg 2016 Dec;123(6):1356-1358

Federman DG, Ladiiznski B, Dardik A, Kelly M, Shapshak D, Ueno CM, Mostow EN, Richmond NA, Hopf HW, Wound Healing Society 2014 update on guidelines for arterial ulcers. Wound Repair Regen 2016 Jan-Feb;24(1):127-35

Hopf HW, Bacterial reservoirs in the operating room. Anesth Analg 2015 Apr;120(4):700-2

Hopf HW, Perioperative temperature management: time for a new standard of care? Anesthesiology 2015 Feb;122(2):229-30

Linden R, Ledez K, Hopf H, Fife C, Topical oxygen therapy is not hyperbaric therapy and the two treatments should not be confused. Int Wound J 2014 Apr;11(2):230-1

Hopf HW, Gordillo G, Intraoperative management and pressure ulcers: not where the problem lies? Crit Care Med 2014 Jan;42(1):199-200

Lee JP, Hopf HW, Cannon-Albright LA, Empiric evidence for a genetic contribution to predisposition to surgical site infection. Wound Repair Regen 2013 Mar-Apr;21(2):211-5

Gertsch MC, Mackintosh N, Hopf HW, In reply. Anesthesiology 2013 Mar;118(3):756-7

Gordillo GM, Bernatchez SF, Diegelmann R, Di Pietro LA, Eriksson E, Hinz B, Hopf HW, Kirsner R, Liu P, Parnell LK, Sandusky GE, Sen CK, Tomic-Canic M, Volk SW, Baird A, Preclinical Models of Wound Healing: Is Man the Model? Proceedings of the Wound Healing Society Symposium. Adv Wound Care (New Rochelle) 2013 Feb;2(1):1-4

Mecham EM, Hopf HW, In reply. Anesthesiology 2012 Oct;117(4):923

Mackintosh N, Gertsch MC, Hopf HW, Pace NL, White J, Morris R, Morrissey C, Wilding V, Herway S, High intraoperative inspired oxygen does not increase postoperative supplemental oxygen requirements. Anesthesiology 2012 Aug;117(2):271-9

Mecham EM, Hopf HW, A proposal to minimize work area contamination during induction. Anesthesiology 2012 Mar;116(3):712

Hunt TK, Hopf HW, Selection of bundle components. Arch Surg 2011 Oct;146(10):1220-1

Feiner JR, Finlay-Morreale HE, Toy P, Lieberman JA, Viele MK, Hopf HW, Weiskopf RB, High Oxygen Partial Pressure Decreases Anemia-induced Heart Rate Increase Equivalent to Transfusion. Anesthesiology 2011 Sep;115(3):492-498

Hopf HW, Rollins MD, Reducing Perioperative Infection Is as Simple as Washing Your Hands. Anesthesiology 2009 Apr 6;:

Hopf HW, Holm J, Hyperoxia and infection. Best Pract Res Clin Anaesthesiol 2008 Sep;22(3):553-69

Hopf HW, Ueno C, Aslam R, Dardik A, Fife C, Grant L, Holloway A, Iafrati MD, Misare B, Rosen N, Shapshak D, Slade JB Jr, West J, Barbul A, Guidelines for the prevention of lower extremity arterial ulcers. Wound Repair Regen 2008 Mar-Apr;16(2):175-88

Wong VK, Stotts NA, Hopf HW, Froelicher ES, Dowling GA, How heel oxygenation changes under pressure. Wound Repair Regen 2007 Nov-Dec;15(6):786-94

Hopf HW, Rollins MD, Wounds: an overview of the role of oxygen. Antioxid Redox Signal 2007 Aug;9(8):1183-92

Hopf HW, Is it time to retire high-concentration nitrous oxide? Anesthesiology 2007 Aug;107(2):200-1

Fukaya E, Hopf HW, HBO and gas embolism. Neurol Res 2007 Mar;29(2):142-5

Hopf HW, Ueno C, Aslam R, Burnand K, Fife C, Grant L, Holloway A, Iafrati MD, Mani R, Misare B, Rosen N, Shapshak D, Benjamin Slade J Jr, West J, Barbul A, Guidelines for the treatment of arterial insufficiency ulcers. Wound Repair Regen 2006 Nov-Dec;14(6):693-710

Ueno C, Hunt TK, Hopf HW, Using physiology to improve surgical wound outcomes. Plast Reconstr Surg 2006 Jun;117(7 Suppl):59S-71S

Weiskopf RB, Feiner J, Hopf H, Lieberman J, Finlay HE, Quah C, Kramer JH, Bostrom A, Toy P, Fresh blood and aged stored blood are equally efficacious in immediately reversing anemia-induced brain oxygenation deficits in humans. Anesthesiology 2006 May;104(5):911-20

Rollins MD, Gibson JJ, Hunt TK, Hopf HW, Wound oxygen levels during hyperbaric oxygen treatment in healing wounds. Undersea Hyperb Med 2006 Jan-Feb;33(1):17-25

Rosen NA, Hopf HW, Hunt TK, Perflubron emulsion increases subcutaneous tissue oxygen tension in rats. Wound Repair Regen 2006 Jan-Feb;14(1):55-60

Hopf HW, Gibson JJ, Angeles AP, Constant JS, Feng JJ, Rollins MD, Zamirul Hussain M, Hunt TK, Hyperoxia and angiogenesis. Wound Repair Regen 2005 Nov-Dec;13(6):558-64

Stotts NA, Hopf HW, Facilitating positive outcomes in older adults with wounds. Nurs Clin North Am 2005 Jun;40(2):267-79

Weiskopf RB, Toy P, Hopf HW, Feiner J, Finlay HE, Takahashi M, Bostrom A, Songster C, Aminoff MJ, Acute isovolemic anemia impairs central processing as determined by P300 latency. Clin Neurophysiol 2005 May;116(5):1028-32

Hopf HW, Hunt TK, Scheuenstuhl H, West JM, Humphrey LM, Rollins MD, Measuring oxygen in wounds. Methods Enzymol 2004;381:539-64

Hopf HW, Development of subcutaneous wound oxygen measurement in humans: contributions of Thomas K Hunt, MD. Wound Repair Regen 2003 Nov-Dec;11(6):424-30

Weiskopf RB, Aminoff MJ, Hopf HW, Feiner J, Viele MK, Watson JJ, Ho R, Songster C, Toy P, Acute isovolemic anemia does not impair peripheral or central nerve conduction. Anesthesiology 2003 Sep;99(3):546-51

Hopf HW, Molecular diagnostics of injury and repair responses in critical illness: what is the future of "monitoring" in the intensive care unit? Crit Care Med 2003 Aug;31(8 Suppl):S518-23

Lin LH, Hopf HW, Paradigm of the injury-repair continuum during critical illness. Crit Care Med 2003 Aug;31(8 Suppl):S493-5

Rollins MD, Conrad MB, Hunt TK, Hopf HW, Accuracy of a polarographic electrode at high oxygen concentrations. Adv Exp Med Biol 2003;510:169-73

Helbich TH, Roberts TP, Rollins MD, Shames DM, Turetschek K, Hopf HW, Mühler M, Hunt TK, Brasch RC, Noninvasive assessment of wound-healing angiogenesis with contrast-enhanced MRI. Acad Radiol 2002 May;9 Suppl 1:S145-7

Weiskopf RB, Feiner J, Hopf HW, Viele MK, Watson JJ, Kramer JH, Ho R, Toy P, Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia. Anesthesiology 2002 Apr;96(4):871-7

Hopf HW, Viele M, Watson JJ, Feiner J, Weiskopf R, Hunt TK, Noorani M, Yeap H, Ho R, Toy P, Subcutaneous perfusion and oxygen during acute severe isovolemic hemodilution in healthy volunteers. Arch Surg 2000 Dec;135(12):1443-9

Sheikh AY, Gibson JJ, Rollins MD, Hopf HW, Hussain Z, Hunt TK, Effect of hyperoxia on vascular endothelial growth factor levels in a wound model. Arch Surg 2000 Nov;135(11):1293-7

Leung JM, Weiskopf RB, Feiner J, Hopf HW, Kelley S, Viele M, Lieberman J, Watson J, Noorani M, Pastor D, Yeap H, Ho R, Toy P, Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans. Anesthesiology 2000 Oct;93(4):1004-10

Weiskopf RB, Kramer JH, Viele M, Neumann M, Feiner JR, Watson JJ, Hopf HW, Toy P, Acute severe isovolemic anemia impairs cognitive function and memory in humans. Anesthesiology 2000 Jun;92(6):1646-52

Lenhardt R, Hopf HW, Marker E, Akça O, Kurz A, Scheuenstuhl H, Sessler DI, Perioperative collagen deposition in elderly and young men and women. Arch Surg 2000 Jan;135(1):71-4

Briese V, Müller H, [Diabetes and pregnancy--optimal management] Zentralbl Gynakol 1992;114(3):115-20