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James C. McRea
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Phone: 801 / 641-3311
Office: Comprehensive CMC Outsourcing, LLC

James C. McRea

Principal Partner, Pharmaceutical Chemistry & Medical Devices, CCMCO, LLC
Adjunct Professor, Bioengineering
Physical Pharmaceutics, PhD., University of Utah
Biology, BS., University of Utah

Research

Cardiac Assist Devices; Controlled Drug Delivery Systems; Blood/Plasma Separation Membrane Devices & Selective Sorption Substrates


Selected Publications

Zentner GM, Rathi R, Shih C, McRea JC, Seo MH, Oh H, Rhee BG, Mestecky J, Moldoveanu Z, Morgan M, Weitman S, Biodegradable block copolymers for delivery of proteins and water-insoluble drugs. J Control Release 2001 May 14;72(1-3):203-15

Tao W, Callahan JD, Vertrees RA, Brunston RL Jr, Deyo DJ, McRea JC, Zwischenberger JB, Heparin clearance profiles after systemic anticoagulation using a heparin removal device system. ASAIO J 1997 Nov-Dec;43(6):922-6

Vertress RA, Zwischenberger JB, McRea JC, Tao W, Kurusz M, Conti VR, Reversal of anticoagulation without protamine using a heparin removal device after cardiopulmonary bypass. ASAIO J 1994 Jul-Sep;40(3):M560-4

Heyman PW, Cho CS, McRea JC, Olsen DB, Kim SW, Heparinized polyurethanes: in vitro and in vivo studies. J Biomed Mater Res 1985 Apr;19(4):419-36

Kim SW, Ebert CD, McRea JC, Briggs C, Byun SM, Kim HP, The biological activity of antithrombotic agents immobilized on polymer surfaces. Ann N Y Acad Sci 1983;416:513-24

McRea JC, Ebert CD, Kim SW, Prostaglandin releasing polymers - stability and efficacy. Trans Am Soc Artif Intern Organs 1981;27:511-6

Peters JL, McRea JC, Fukumasu H, Mochizuki T, Daitoh N, McGough E, Pearce M, Fee H, Rich G, Recovery of cardiac function with total transapical left ventricular bypass. Trans Am Soc Artif Intern Organs 1980;26:262-7

Peters JL, McRea JC, Fukumasu H, Iwaya F, Kolff WJ, Transapical left ventricular bypass: a method for partial or total circulatory support. Artif Organs 1978 Aug;2(3):263-7

Peters JL, Fukumasu H, McRea JC, Nakagaki M, Iwaya F, Owen D, Kolff J, Kolff WJ, Prolonged, transapical left ventricular bypass (TALVB) in sheep and man. Trans Am Soc Artif Intern Organs 1978;24:113-21

McRea JC, Kim SW, Characterization of controlled release of prostaglandin from polymer matrices for thrombus prevention. Trans Am Soc Artif Intern Organs 1978;24:746-52

Wong KC, Peters JL, Roberts TS, McRea JC, Fukumasu H, Lack of CNS depression from large doses of trimethaphan in sheep. Anesth Analg 1977 Jan-Feb;56(1):6-8

Peters JL, McRea JC, Fukumasu H, Kolff WJ, Extracorporeal, biventricular bypass (BVB) of the natural heart. Trans Am Soc Artif Intern Organs 1977;23:506-11

McRea JC, Peters JL, Fukumasu H, Blood access system developed for transapical left ventricular bypass (TALVB). Trans Am Soc Artif Intern Organs 1977;23:309-13

Peters JL, McRea JC, Fukumasu H, Kolff WJ, Transapical left ventricular bypass (TALVB) without an auxiliary ventricle. Trans Am Soc Artif Intern Organs 1976;22:357-66

Watanabe K, Kabei N, McRea J, Peters J, Continuous measurement of myocardial oxygen consumption (MVO2) and hemodynamic response during transapical left ventricular bypass (TALVB). Trans Am Soc Artif Intern Organs 1975;21:566-72