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Frederic  Noo

Phone: 801-581-5347
Office: UCAIR, 729 Arapeen

Frederic Noo

Assistant professor of Radiology
Adjunct assistant professor of Electrical and Computer Engineering
Adjunct Professor, Bioengineering
Ph.D. (1998), Applied Sciences (medical imaging), Univ. of Liege, Belgium
M.S (1993), Mechanical Engineering (physics), Univ. of Liege, Belgium


Image reconstruction problems in X-ray computed tomography and nuclear medicine

Current Research

My current research focusses on two main topics:
(i) development of new techniques for accurate X-ray CT imaging, specifically designed to handle limitations in data acquisition capabilties and/or achieve optimal use of radiation exposure
(ii) construction of an accurate mathematical phantom modelling the heart and its use for the development and evaluation of cardiac X-ray CT imaging techniques

Selected Publications

Young S, Lo P, Kim G, Brown M, Hoffman J, Hsu W, Wahi-Anwar W, Flores C, Lee G, Noo F, Goldin J, McNitt-Gray M, The effect of radiation dose reduction on computer-aided detection (CAD) performance in a low-dose lung cancer screening population. Med Phys 2017 Apr;44(4):1337-1346

Hahn K, Schöndube H, Stierstorfer K, Hornegger J, Noo F, A comparison of linear interpolation models for iterative CT reconstruction. Med Phys 2016 Dec;43(12):6455

Noo F, Guo Z, MO-DE-207A-01: Impact of Statistical Weights On Detection of Low-Contrast Details in Model-Based Iterative CT Reconstruction. Med Phys 2016 Jun;43(6):3700

Xu J, Tsui B, Noo F, MO-DE-207A-02: A Feature-Preserving Image Reconstruction Method for Improved Pancreaticlesion Classification in Diagnostic CT Imaging. Med Phys 2016 Jun;43(6):3700

Young S, Hoffman J, Noo F, McNitt-Gray M, SU-F-I-49: Vendor-Independent, Model-Based Iterative Reconstruction On a Rotating Grid with Coordinate-Descent Optimization for CT Imaging Investigations. Med Phys 2016 Jun;43(6):3397-3398

Young S, Lo P, Hoffman J, Wahi-Anwar M, Noo F, Brown M, McNitt-Gray M, TH-AB-207A-05: A Fully-Automated Pipeline for Generating CT Images Across a Range of Doses and Reconstruction Methods. Med Phys 2016 Jun;43(6):3860

Hoffman J, Noo F, Young S, McNitt-Gray M, TH-AB-207A-09: Tailoring TCM Schemes to a Task: Evaluating the Impact of Customized TCM Profiles On Detection of Lung Nodules in Simulated CT Lung Cancer Screening. Med Phys 2016 Jun;43(6):3861-3862

Morey AM, Noo F, Kadrmas DJ, Effect of Using 2mm Voxels on Observer Performance for PET Lesion Detection. IEEE Trans Nucl Sci 2016 Jun;63(3):1359-1366

Hoffman J, Young S, Noo F, McNitt-Gray M, Technical Note: FreeCT_wFBP: A robust, efficient, open-source implementation of weighted filtered backprojection for helical, fan-beam CT. Med Phys 2016 Mar;43(3):1411-20

Yu Z, Lauritsch G, Dennerlein F, Mao Y, Hornegger J, Noo F, Extended ellipse-line-ellipse trajectory for long-object cone-beam imaging with a mounted C-arm system. Phys Med Biol 2016 Feb 21;61(4):1829-51

Young S, Hoffman J, Noo F, McNitt-Gray M, SU-E-I-35: Development of Stand-Alone Filtered Backprojection and Iterative Reconstruction Methods Using the Raw CT Data Exported From Clinical Lung Screening Scans. Med Phys 2015 Jun;42(6):3249

Noo F, Karellas A, Introduction: Advances and trends in image formation in X-ray computed tomography. Med Phys 2015 May;42(5):2656

Noo F, Karellas A, Focus series introduction. X-ray computed tomography: 2012 advances in image formation. Med Phys 2013 Mar;40(3):031001

Wunderlich A, Noo F, New Theoretical Results on Channelized Hotelling Observer Performance Estimation with Known Difference of Class Means. IEEE Trans Nucl Sci 2013 Jan 11;60(1):182-193

Yu Z, Noo F, Dennerlein F, Wunderlich A, Lauritsch G, Hornegger J, Simulation tools for two-dimensional experiments in x-ray computed tomography using the FORBILD head phantom. Phys Med Biol 2012 Jul 7;57(13):N237-52

Wunderlich A, Noo F, On Efficient Assessment of Image-Quality Metrics Based on Linear Model Observers. IEEE Trans Nucl Sci 2012 Jun;59(3):568-578

McNitt-Gray M, Noo F, Fessier J, Samei E, MO-D-BRA-01: Limits of Dose Reduction in CT: Where are They and How Will We Know When We Get There? Med Phys 2012 Jun;39(6Part21):3868

Wunderlich A, Noo F, Confidence intervals for performance assessment of linear observers. Med Phys 2011 Jul;38 Suppl 1:S57

Noo F, Karellas A, X-ray computed tomography: advances in image formation. Med Phys 2011 Jul;38 Suppl 1:S1

Wunderlich A, Noo F, Confidence intervals for performance assessment of linear observers. Med Phys 2011 Jul;38(S1):S57-S68

Dennerlein F, Noo F, Cone-beam artifact evaluation of the factorization method. Med Phys 2011 Jul;38(S1):S18-S24

Noo F, Karellas A, X-ray computed tomography: Advances in image formation. Med Phys 2011 Jul;38(S1):S1

Yu Z, Wunderlich A, Dennerlein F, Lauritsch G, Noo F, Line plus arc source trajectories and their R-line coverage for long-object cone-beam imaging with a C-arm system. Phys Med Biol 2011 Jun 21;56(12):3447-71

Wunderlich A, Noo F, Band-restricted estimation of noise variance in filtered backprojection reconstructions using repeated scans. IEEE Trans Med Imaging 2010 May;29(5):1097-113

Schöndube H, Stierstorfer K, Noo F, Exact Efficient Handling of Interrupted Illumination in Helical Cone-Beam Computed Tomography with Arbitrary Pitch. Tsinghua Sci Technol 2010 Feb;15(1):36-43

Schöndube H, Stierstorfer K, Noo F, Accurate helical cone-beam CT reconstruction with redundant data. Phys Med Biol 2009 Aug 7;54(15):4625-44

Wunderlich A, Noo F, Estimation of channelized hotelling observer performance with known class means or known difference of class means. IEEE Trans Med Imaging 2009 Aug;28(8):1198-207

Wunderlich A, Noo F, Image covariance and lesion detectability in direct fan-beam x-ray computed tomography. Phys Med Biol 2008 May 21;53(10):2471-93

Wunderlich A, Noo F, Evaluation of image noise in fan-beam x-ray computed tomography. Conf Proc IEEE Eng Med Biol Soc 2008;2008:2713-6

Wunderlich A, Noo F, Evaluation of the impact of tube current modulation on lesion detectability using model observers. Conf Proc IEEE Eng Med Biol Soc 2008;2008:2705-8

Dennerlein F, Noo F, Schöndube H, Lauritsch G, Hornegger J, A factorization approach for cone-beam reconstruction on a circular short-scan. IEEE Trans Med Imaging 2008;27(7):887-96

Noo F, Hoppe S, Dennerlein F, Lauritsch G, Hornegger J, A new scheme for view-dependent data differentiation in fan-beam and cone-beam computed tomography. Phys Med Biol 2007 Sep 7;52(17):5393-414

Dennerlein F, Noo F, Hornegger J, Lauritsch G, Fan-beam filtered-backprojection reconstruction without backprojection weight. Phys Med Biol 2007 Jun 7;52(11):3227-40

Zhang L, Chapman BE, Parker DL, Roberts JA, Guo J, Vemuri P, Moon SM, Noo F, Automatic detection of three-dimensional vascular tree centerlines and bifurcations in high-resolution magnetic resonance angiography. Invest Radiol 2005 Oct;40(10):661-71

Pack JD, Noo F, Clackdoyle R, Cone-beam reconstruction using the backprojection of locally filtered projections. IEEE Trans Med Imaging 2005 Jan;24(1):70-85

Noo F, Clackdoyle R, Pack JD, A two-step Hilbert transform method for 2D image reconstruction. Phys Med Biol 2004 Sep 7;49(17):3903-23

Noo F, Defrise M, Kudo H, General reconstruction theory for multislice X-ray computed tomography with a gantry tilt. IEEE Trans Med Imaging 2004 Sep;23(9):1109-16

Pack JD, Noo F, Kudo H, Investigation of saddle trajectories for cardiac CT imaging in cone-beam geometry. Phys Med Biol 2004 Jun 7;49(11):2317-36

Noo F, Pack J, Heuscher D, Exact helical reconstruction using native cone-beam geometries. Phys Med Biol 2003 Dec 7;48(23):3787-818

Noo F, Clackdoyle R, Wagner JM, Inversion of the 3D exponential x-ray transform for a half equatorial band and other semi-circular geometries. Phys Med Biol 2002 Aug 7;47(15):2727-35

Noo F, Defrise M, Clackdoyle R, Kudo H, Image reconstruction from fan-beam projections on less than a short scan. Phys Med Biol 2002 Jul 21;47(14):2525-46

Mennessier C, Noo F, Clackdoyle R, Bal G, Desbat L, Attenuation correction in SPECT using consistency conditions for the exponential ray transform. Phys Med Biol 1999 Oct;44(10):2483-510

Noo F, Defrise M, Clackdoyle R, Single-slice rebinning method for helical cone-beam CT. Phys Med Biol 1999 Feb;44(2):561-70