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Richard Daniel King
E-mail:

Phone: 801-581-7637
Phone: 801-585-6546
Office: 417 Wakara Way #2210

Richard Daniel King

Director, Alzheimer's Image Analysis Laboratory
Assistant Professor of Neurology
Adjunct Assistant Professor, Bioengineering
Center for Alzheimer's Care, Imaging, and Research
2002 Rich Dickason Outstanding Physician Scientist Award
Alpha Man of the Year
BS, Engineering, Texas A&M University, 1994
PhD, Neuroscience, Baylor College of Medicine, 2000
MD, Baylor College of Medicine, 2002
Neurology Residency, Harvard Medical School, 2006

Lab

Alzheimer's Image Analysis Laboratory


Research

Magnetic Resonance Images, Alzheimer


Current Research

Dr. King's research uses multi-disciplinary translational approaches to understand Alzheimer's disease and related neurodegenerative disorders. His current focus is the use of advanced neuroimaging analysis tools to study morphometric changes in the brain associated with neurodegenerative diseases.

One area of focus is applying a novel method of computing cerebral cortical complexity known as fractal analysis. This technique is applied to high-resolution, high-contrast MR images to quantitatively characterize changes in the shape of the cerebral cortex caused by atrophy. Such changes in cortical shape could be useful for early detection of Alzheimer's and other neurologic diseases. These tools could be used as a surrogate biomarker for disease progression or as a metric for the success of therapeutic interventions. Dr. King will study the application of fractal analysis and other neuroimaging analysis tools in the new Alzheimer's Image Analysis Laboratory, which was designed to be a shared resource for the University of Utah imaging community.


Selected Publications

Singh N, Fletcher PT, Preston JS, King RD, Marron JS, Weiner MW, Joshi S, Quantifying anatomical shape variations in neurological disorders. Med Image Anal 2014 Apr;18(3):616-33

King RD, Brown B, Hwang M, Jeon T, George AT, Fractal dimension analysis of the cortical ribbon in mild Alzheimer's disease. Neuroimage 2010 Nov 1;53(2):471-9

Warner MA, Youn TS, Davis T, Chandra A, Marquez de la Plata C, Moore C, Harper C, Madden CJ, Spence J, McColl R, Devous M, King RD, Diaz-Arrastia R, Regionally Selective Atrophy After Traumatic Axonal Injury. Arch Neurol 2010 Jul 30;: