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Roy  Bloebaum

Roy Bloebaum

Selected Publications

Tucker JJ, Gordon JA, Zanes RC, Zuskov A, Vinciguerra JD, Bloebaum RD, Soslowsky LJ, P2 porous titanium implants improve tendon healing in an acute rat supraspinatus repair model. J Shoulder Elbow Surg 2017 Mar;26(3):529-535

Bloebaum RD, Abdo NT, Hofmann AA, Epperson RT, Olsen RE, Chalayon O, Transcortical or intracondylar? Which model is accurate for predicting biomaterial attachment in total joint replacement? J Biomed Mater Res B Appl Biomater 2017 Feb 28;:

Bloebaum RD, Letter to the Editor: Editorial: The Graying of the (Funded) Musculoskeletal Scientist. Clin Orthop Relat Res 2016 Nov;474(11):2543

Isaacson BM, Potter BK, Bloebaum RD, Epperson RT, Kawaguchi BS, Swanson TM, Pasquina PF, Link Between Clinical Predictors of Heterotopic Ossification and Histological Analysis in Combat-Injured Service Members. J Bone Joint Surg Am 2016 Apr 20;98(8):647-57

Skedros JG, Keenan KE, Cooper DML, Bloebaum RD, Histocompositional organization and toughening mechanisms in antler. J Struct Biol 2014 Aug;187(2):129-148

Williams DL, Lerdahl JM, Haymond BS, Bloebaum RD, In vitro efficacy of a novel active-release antimicrobial coating to eradicate biofilms of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2014;58(4):2400-4

Sinclair KD, Pham TX, Williams DL, Farnsworth RW, Loc-Carrillo CM, Bloebaum RD, Model development for determining the efficacy of a combination coating for the prevention of perioperative device related infections: a pilot study. J Biomed Mater Res B Appl Biomater 2013 Oct;101(7):1143-53

Williams DL, Sinclair KD, Jeyapalina S, Bloebaum RD, Characterization of a novel active release coating to prevent biofilm implant-related infections. J Biomed Mater Res B Appl Biomater 2013 Aug;101(6):1078-89

Holt BM, Bachus KN, Beck JP, Bloebaum RD, Jeyapalina S, Immediate post-implantation skin immobilization decreases skin regression around percutaneous osseointegrated prosthetic implant systems. J Biomed Mater Res A 2013 Jul;101(7):2075-82

Sinclair SK, Bell S, Epperson RT, Bloebaum RD, The significance of calcified fibrocartilage on the cortical endplate of the translational sheep spine model. Anat Rec (Hoboken) 2013 May;296(5):736-44

Sinclair KD, Farnsworth RW, Pham TX, Knight AN, Bloebaum RD, Skedros JG, The artiodactyl calcaneus as a potential 'control bone' cautions against simple interpretations of trabecular bone adaptation in the anthropoid femoral neck. J Hum Evol 2013 May;64(5):366-79

Williams DL, Haymond BS, Beck JP, Savage PB, Chaudhary V, Epperson RT, Kawaguchi B, Bloebaum RD, In vivo efficacy of a silicone?cationic steroid antimicrobial coating to prevent implant-related infection. Biomaterials 2012 Nov;33(33):8641-56

Sinclair KD, Pham TX, Farnsworth RW, Williams DL, Loc-Carrillo C, Horne LA, Ingebretsen SH, Bloebaum RD, Development of a broad spectrum polymer-released antimicrobial coating for the prevention of resistant strain bacterial infections. J Biomed Mater Res A 2012 Oct;100(10):2732-8

Jeyapalina S, Beck JP, Bachus KN, Bloebaum RD, Cortical bone response to the presence of load-bearing percutaneous osseointegrated prostheses. Anat Rec (Hoboken) 2012 Sep;295(9):1437-45

Jeyapalina S, Beck JP, Bachus KN, Williams DL, Bloebaum RD, Efficacy of a porous-structured titanium subdermal barrier for preventing infection in percutaneous osseointegrated prostheses. J Orthop Res 2012 Aug;30(8):1304-11

Williams DL, Haymond BS, Woodbury KL, Beck JP, Moore DE, Epperson RT, Bloebaum RD, Experimental model of biofilm implant-related osteomyelitis to test combination biomaterials using biofilms as initial inocula. J Biomed Mater Res A 2012 Jul;100(7):1888-900

Bloebaum RD, Koller KE, Willie BM, Hofmann AA, Does using autograft bone chips achieve consistent bone ingrowth in primary TKA? Clin Orthop Relat Res 2012 Jul;470(7):1869-78

Sinclair SK, Konz GJ, Dawson JM, Epperson RT, Bloebaum RD, Host bone response to polyetheretherketone versus porous tantalum implants for cervical spinal fusion in a goat model. Spine (Phila Pa 1976) 2012 May 1;37(10):E571-80

Skedros JG, Knight AN, Farnsworth RW, Bloebaum RD, Do regional modifications in tissue mineral content and microscopic mineralization heterogeneity adapt trabecular bone tracts for habitual bending? Analysis in the context of trabecular architecture of deer calcanei. J Anat 2012 Mar;220(3):242-55

Shelton TJ, Beck JP, Bloebaum RD, Bachus KN, Percutaneous osseointegrated prostheses for amputees: Limb compensation in a 12-month ovine model. J Biomech 2011 Oct 13;44(15):2601-6

Williams DL, Woodbury KL, Haymond BS, Parker AE, Bloebaum RD, A modified CDC biofilm reactor to produce mature biofilms on the surface of peek membranes for an in vivo animal model application. Curr Microbiol 2011 Jun;62(6):1657-63

Isaacson BM, Brown AA, Brunker LB, Higgins TF, Bloebaum RD, Clarifying the structure and bone mineral content of heterotopic ossification. J Surg Res 2011 May 15;167(2):e163-70

Sinclair KD, Curtis BD, Koller KE, Bloebaum RD, Characterization of the anchoring morphology and mineral content of the anterior cruciate and medial collateral ligaments of the knee. Anat Rec (Hoboken) 2011 May;294(5):831-8

Isaacson BM, Brunker LB, Brown AA, Beck JP, Burns GL, Bloebaum RD, An evaluation of electrical stimulation for improving periprosthetic attachment. J Biomed Mater Res B Appl Biomater 2011 Apr;97(1):190-200

Isaacson BM, Bloebaum RD, Bone bioelectricity: what have we learned in the past 160 years? J Biomed Mater Res A 2010 Dec 15;95(4):1270-9

Williams DL, Bloebaum RD, Beck JP, Petti CA, Characterization of bacterial isolates collected from a sheep model of osseointegration. Curr Microbiol 2010 Dec;61(6):574-83

Chou TG, Petti CA, Szakacs J, Bloebaum RD, Evaluating antimicrobials and implant materials for infection prevention around transcutaneous osseointegrated implants in a rabbit model. J Biomed Mater Res A 2010 Mar 1;92(3):942-52

Perry EL, Beck JP, Williams DL, Bloebaum RD, Assessing peri-implant tissue infection prevention in a percutaneous model. J Biomed Mater Res B Appl Biomater 2010 Feb;92(2):397-408

Isaacson BM, Stinstra JG, MacLeod RS, Webster JB, Beck JP, Bloebaum RD, Bioelectric analyses of an osseointegrated intelligent implant design system for amputees. J Vis Exp 2009 Jul 15;(29):1-6

Isaacson BM, Vance RE, Chou TG, Bloebaum RD, Bachus KN, Webster JB, Effectiveness of resonance frequency in predicting orthopedic implant strength and stability in an in vitro osseointegration model. J Rehabil Res Dev 2009;46(9):1109-20

Rosenbaum Chou TG, Child JR, Naughtin RJ, Rigdon RR, Schumann C, Bloebaum RD, The relationship between femoral periprosthetic cortical bone geometry and porosity after total hip arthroplasty. J Biomed Mater Res A 2008 Oct;87(1):107-15

Williams D, Bloebaum R, Petti CA, Characterization of Staphylococcus aureus strains in a rabbit model of osseointegrated pin infections. J Biomed Mater Res A 2008 May;85(2):366-70

Willie BM, Foot LJ, Prall MW, Bloebaum RD, Examining the influence of short-term implantation on oxidative degradation in retrieved highly crosslinked polyethylene tibial components. J Biomed Mater Res B Appl Biomater 2008 May;85(2):385-97

Willie BM, Foot LJ, Prall MW, Bloebaum RD, Surface damage analysis of retrieved highly crosslinked polyethylene tibial components after short-term implantation. J Biomed Mater Res B Appl Biomater 2008 Apr;85(1):114-24

Bloebaum RD, Willie BM, Mitchell BS, Hofmann AA, Relationship between bone ingrowth, mineral apposition rate, and osteoblast activity. J Biomed Mater Res A 2007 May;81(2):505-14

Bloebaum RD, Higgins HW 2nd, Koller KE, A Method for Cemented Bone Interface Examination Without Polymethylmethacrylate Embedment. J Histotechnol 2006 Dec;29(4):229-231

Hofmann AA, Bloebaum RD, Koller KE, Lahav A, Does celecoxib have an adverse effect on bone remodeling and ingrowth in humans? Clin Orthop Relat Res 2006 Nov;452:200-4

Skedros JG, Dayton MR, Sybrowsky CL, Bloebaum RD, Bachus KN, The influence of collagen fiber orientation and other histocompositional characteristics on the mechanical properties of equine cortical bone. J Exp Biol 2006 Aug;209(Pt 15):3025-42

Peters CL, Hines JL, Bachus KN, Craig MA, Bloebaum RD, Biological effects of calcium sulfate as a bone graft substitute in ovine metaphyseal defects. J Biomed Mater Res A 2006 Mar 1;76(3):456-62

Rosenbaum TG, Hamblin T, Bloebaum RD, Determining the degree of cortical bone asymmetry in bilateral, nonpathological, human femur pairs. J Biomed Mater Res A 2006 Mar 1;76(3):450-5

Bloebaum RD, Holmes JL, Skedros JG, Mineral content changes in bone associated with damage induced by the electron beam. Scanning 2005 Sep-Oct;27(5):240-8

Skedros JG, Holmes JL, Vajda EG, Bloebaum RD, Cement lines of secondary osteons in human bone are not mineral-deficient: new data in a historical perspective. Anat Rec A Discov Mol Cell Evol Biol 2005 Sep;286(1):781-803

Bloebaum RD, Lundeen GA, Shea JE, Whitaker EL, Age-related mineralization heterogeneity changes in trabecular bone of the proximal femur. Anat Rec A Discov Mol Cell Evol Biol 2004 Dec;281(2):1296-302

Bloebaum RD, Ferguson RP, Neff CM, Van Gorp C, Woolley DL, Hofmann AA, Bone viability determination in human cancellous bone from patients undergoing revision hip arthroplasty. J Arthroplasty 2004 Sep;19(6):745-50

Bloebaum RD, Kopp DV, Remodeling capacity of calcified fibrocartilage of the hip. Anat Rec A Discov Mol Cell Evol Biol 2004 Aug;279(2):736-9

Willie BM, Watts CW, Szakacs JG, Bloebaum RD, A comparative staining technique to detect mineral oil contaminants from orthopedic implants. J Biomed Mater Res B Appl Biomater 2004 Jul 15;70(1):130-8

Willie BM, Bloebaum RD, Bireley WR, Bachus KN, Hofmann AA, Determining relevance of a weight-bearing ovine model for bone ingrowth assessment. J Biomed Mater Res A 2004 Jun 1;69(3):567-76

Willie BM, Ashrafi S, Alajbegovic S, Burnett T, Bloebaum RD, Quantifying the effect of resin type and sterilization method on the degradation of ultrahigh molecular weight polyethylene after 4 years of real-time shelf aging. J Biomed Mater Res A 2004 Jun 1;69(3):477-89

Skedros JG, Hunt KJ, Bloebaum RD, Relationships of loading history and structural and material characteristics of bone: development of the mule deer calcaneus. J Morphol 2004 Mar;259(3):281-307

Skedros JG, Sybrowsky CL, Parry TR, Bloebaum RD, Regional differences in cortical bone organization and microdamage prevalence in Rocky Mountain mule deer. Anat Rec A Discov Mol Cell Evol Biol 2003 Sep;274(1):837-50

Skedros JG, Dayton MR, Sybrowsky CL, Bloebaum RD, Bachus KN, Are uniform regional safety factors an objective of adaptive modeling/remodeling in cortical bone? J Exp Biol 2003 Jul;206(Pt 14):2431-9

Kuo TY, Skedros JG, Bloebaum RD, Measurement of femoral anteversion by biplane radiography and computed tomography imaging: comparison with an anatomic reference. Invest Radiol 2003 Apr;38(4):221-9

Shea JE, Hallows RK, Ricks S, Bloebaum RD, Microvascularization of the hypermineralized calcified fibrocartilage and cortical bone in the sheep proximal femur. Anat Rec 2002 Dec 1;268(4):365-70

Brodke DS, Willie BM, Maaranen EA, Bloebaum RD, Spinal cage retrieval and assessment of biologic response. J Spinal Disord Tech 2002 Jun;15(3):206-12

Skedros JG, Mason MW, Bloebaum RD, Modeling and remodeling in a developing artiodactyl calcaneus: a model for evaluating Frost's Mechanostat hypothesis and its corollaries. Anat Rec 2001 Jun 1;263(2):167-85

Willie BM, Gingell DT, Bloebaum RD, Hofmann AA, Possible explanation for the white band artifact seen in clinically retrieved polyethylene tibial components. J Biomed Mater Res 2000 Dec 5;52(3):558-66

Holmes JL, Bachus KN, Bloebaum RD, Thermal effects of the electron beam and implications of surface damage in the analysis of bone tissue. Scanning 2000 Jul-Aug;22(4):243-8

Vajda EG, Humphrey S, Skedros JG, Bloebaum RD, Influence of topography and specimen preparation on backscattered electron images of bone. Scanning 1999 Nov-Dec;21(6):379-87

Lundeen GA, Vajda EG, Bloebaum RD, Age-related cancellous bone loss in the proximal femur of caucasian females. Osteoporos Int 2000;11(6):505-11

Su SC, Skedros JG, Bachus KN, Bloebaum RD, Loading conditions and cortical bone construction of an artiodactyl calcaneus. J Exp Biol 1999 Nov;202(Pt 22):3239-54

Bachus KN, Bloebaum RD, Jones RE, Comparative micromotion of fully and proximally cemented femoral stems. Clin Orthop Relat Res 1999 Sep;(366):248-57

Vajda EG, Bloebaum RD, Age-related hypermineralization in the female proximal human femur. Anat Rec 1999 Jun 1;255(2):202-11

Vajda EG, Skedros JG, Bloebaum RD, Errors in quantitative backscattered electron analysis of bone standardized by energy-dispersive x-ray spectrometry. Scanning 1998 Oct;20(7):527-35

Kuo TY, Skedros JG, Bloebaum RD, Comparison of human, primate, and canine femora: implications for biomaterials testing in total hip replacement. J Biomed Mater Res 1998 Jun 5;40(3):475-89

Bloebaum RD, Bachus KN, Jensen JW, Scott DF, Hofmann AA, Porous-coated metal-backed patellar components in total knee replacement. A postmortem retrieval analysis. J Bone Joint Surg Am 1998 Apr;80(4):518-28

Bloebaum RD, Lundeen GA, Bachus KN, Ison I, Hofmann AA, Dissolution of particulate hydroxyapatite in a macrophage organelle model. J Biomed Mater Res 1998 Apr;40(1):104-14

Lundeen GA, Shea KG, Sanderson C, Bachus KN, Bloebaum RD, Technique for identification of submicron metal particulate from implants in histological specimens. J Biomed Mater Res 1998 Summer;43(2):168-74

Skedros JG, Su SC, Bloebaum RD, Biomechanical implications of mineral content and microstructural variations in cortical bone of horse, elk, and sheep calcanei. Anat Rec 1997 Nov;249(3):297-316

Bloebaum RD, Mihalopoulus NL, Jensen JW, Dorr LD, Postmortem analysis of bone growth into porous-coated acetabular components. J Bone Joint Surg Am 1997 Jul;79(7):1013-22

Shea KG, Lundeen GA, Bloebaum RD, Bachus KN, Zou L, Lymphoreticular dissemination of metal particles after primary joint replacements. Clin Orthop Relat Res 1997 May;(338):219-26

Hofmann AA, Bloebaum RD, Bachus KN, Progression of human bone ingrowth into porous-coated implants. Rate of bone ingrowth in humans. Acta Orthop Scand 1997 Apr;68(2):161-6

Parkin JL, Bloebaum R, Parkin BD, Parkin MJ, Osseointegration and growth effects of temporal bone percutaneous pedestals. Am J Otol 1996 Sep;17(5):735-42

Shea KG, Bloebaum RD, Avent JM, Birk T, Samuelson KA, Analysis of lymph nodes for polyethylene particles in patients who have had a primary joint replacement. J Bone Joint Surg Am 1996 Apr;78(4):497-504

Shea KG, Lundeen GA, Bachus KN, Bloebaum RD, Dunn HK, Inability of energy dispersive X-ray analysis to identify particulate polyethylene. J Biomed Mater Res 1996 Feb;30(2):175-80

Edelson R, Burks RT, Bloebaum RD, Short-term effects of knee washout for osteoarthritis. Am J Sports Med 1995 May-Jun;23(3):345-9

McDonald MD, Bloebaum RD, Distinguishing wear and creep in clinically retrieved polyethylene inserts. J Biomed Mater Res 1995 Jan;29(1):1-7

Savory KM, Hutchinson DT, Bloebaum R, Materials testing protocol for small joint prostheses. J Biomed Mater Res 1994 Oct;28(10):1209-19

Skedros JG, Mason MW, Bloebaum RD, Differences in osteonal micromorphology between tensile and compressive cortices of a bending skeletal system: indications of potential strain-specific differences in bone microstructure. Anat Rec 1994 Aug;239(4):405-13

Skedros JG, Bloebaum RD, Mason MW, Bramble DM, Analysis of a tension/compression skeletal system: possible strain-specific differences in the hierarchical organization of bone. Anat Rec 1994 Aug;239(4):396-404

Schneiderman G, Meldrum RD, Bloebaum RD, Tarr R, Sarmiento A, The interosseous membrane of the forearm: structure and its role in Galeazzi fractures. J Trauma 1993 Dec;35(6):879-85

Bloebaum RD, Ota DT, Skedros JG, Mantas JP, Comparison of human and canine external femoral morphologies in the context of total hip replacement. J Biomed Mater Res 1993 Sep;27(9):1149-59

Skedros JG, Bloebaum RD, Bachus KN, Boyce TM, The meaning of graylevels in backscattered electron images of bone. J Biomed Mater Res 1993 Jan;27(1):47-56

Bloebaum RD, Rubman MH, Merrell M, Thacker K, Hofmann AA, Hyaluronan solution as a cartilage antidesiccant. J Biomed Mater Res 1992 Mar;26(3):303-17

Bloebaum RD, Nelson K, Dorr LD, Hofmann AA, Lyman DJ, Investigation of early surface delamination observed in retrieved heat-pressed tibial inserts. Clin Orthop Relat Res 1991 Aug;(269):120-7

Bloebaum RD, Rhodes DM, Rubman MH, Hofmann AA, Bilateral tibial components of different cementless designs and materials. Microradiographic, backscattered imaging, and histologic analysis. Clin Orthop Relat Res 1991 Jul;(268):179-87

Bloebaum RD, Merrell M, Gustke K, Simmons M, Retrieval analysis of a hydroxyapatite-coated hip prosthesis. Clin Orthop Relat Res 1991 Jun;(267):97-102

Bloebaum RD, Sanderson CA, Emmanual J, Campbell P, Emmanual J, Yocham GD, Histological analysis of a central tarsal implant in a racing greyhound. Vet Rec 1989 Apr 1;124(13):339-42