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Masaaki  Yoshigi

Phone: 801-585-0663
Office: 2A152 SOM

Masaaki Yoshigi

Assistant Professor in Pediatric Administration
Adjunct Assistant Professor, Bioengineering

Selected Publications

Hoffman L, Jensen CC, Yoshigi M, Beckerle M, Mechanical signals activate p38 MAPK pathway-dependent reinforcement of actin via mechanosensitive HspB1. Mol Biol Cell 2017 Oct 1;28(20):2661-2675

Yoshigi M, Pronovost SM, Kadrmas JL, Interactions by 2D Gel Electrophoresis Overlap (iGEO): a novel high fidelity approach to identify constituents of protein complexes. Proteome Sci 2013 May 12;11(1):21

Hoffman LM, Jensen CC, Chaturvedi A, Yoshigi M, Beckerle MC, Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators. Mol Biol Cell 2012 May;23(10):1846-59

Eisenhoffer GT, Loftus PD, Yoshigi M, Otsuna H, Chien CB, Morcos PA, Rosenblatt J, Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia. Nature 2012 Apr 15;484(7395):546-9

Balanis N, Yoshigi M, Wendt MK, Schiemann WP, Carlin CR, {beta}3 Integrin-EGF Receptor Crosstalk Activates p190RhoGAP in Mouse Mammary Gland Epithelial Cells. Mol Biol Cell 2011 Sep 21;:

Lilly B, Clark KA, Yoshigi M, Pronovost S, Wu ML, Periasamy M, Chi M, Paul RJ, Yet SF, Beckerle MC, Loss of the serum response factor cofactor, cysteine-rich protein 1, attenuates neointima formation in the mouse. Arterioscler Thromb Vasc Biol 2010 Apr;30(4):694-701

Hoffman LM, Jensen CC, Kloeker S, Wang CL, Yoshigi M, Beckerle MC, Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling. J Cell Biol 2006 Feb 27;172(5):771-82

Yoshigi M, Hoffman LM, Jensen CC, Yost HJ, Beckerle MC, Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement. J Cell Biol 2005 Oct 24;171(2):209-15

Yoshigi M, Clark EB, Yost HJ, Quantification of stretch-induced cytoskeletal remodeling in vascular endothelial cells by image processing. Cytometry A 2003 Oct;55(2):109-18